I know where mine originate from. I don't know if my issues all stem from PsA or are separate issues no doctor has told me yet, but I have DDD, Stenosis and scoliosis. Since right after Thanksgiving and right after I had bronchitis, my knees, backs of my legs and buttocks just hurt, burn and down right painful. Walking with 2 canes. I have nerve inpengment from the stenosis and think that this is what all the pain in tendons, knees and muscles is from., but I think the bronchitis got my immune system ramped up and now it won't shut off. I have been off Enbrel for 7 months and until I got sick was doing fine. I am hanging in there until I see my doc in Feb. To answer your question I would say a big YES. AS, PsA all of the related diseases has everything to do with what we are feeling. And add the cold temps and weather we all are having.