This disease has had a huge impact on our family. My 27 year old daughter has been diagnosed now for about 14 years, my 16 year old was recently diagnosed and now my husband. They are all HLA-B27 positive. Really looking for a doctor that will entertain cardiac involvement. 16 year old and husband have been having issues with elevated heart rates, 16 year old did see a cardiologist who after doing some research and evaluating my 27 year old's history,(she suffered heart failure at 14) stated she does feel AS caused the 27 year old's heart issues and that we should monitor younger daughter and husband. However, she feels this should be directed by a rheumatologist.