Hi! I'm 22 and I have AS too (diagnosed at 15). I was diagnosed with Crohn's at 19. I was on Simponi at the time, which wasn't used for Crohn's, so was switched to Remicade and Methotrexate. It worked well for my Crohn's (less well for my AS) and my Crohn's was in remission for 3 years.
Now I'm on Cosentyx, which does not treat the Crohn's but does treat the AS. My AS has always been much MUCH worse than my Crohn's so we felt trying Cosentyx was worth the risk. Within a couple months, my Crohn's flared and we're still figuring out how to treat it, since Cosentyx is really working for my AS.
There are other options for Crohn's, if she doesn't want to switch biologics. I'm currently on Imuran and Entocort for the Crohn's. 6MP is another option. Methotrexate is also used for Crohn's.
However, biologics work the best and that's probably why they want her to switch. I know for me, anti-TNFs put the Crohn's in remission, while just Imuran did not.
My rheumatologist and GI really work together to manage my care though sometimes it is hard to get them to communicate with each other.
Unfortunately, there is no real way to know if Humira will work for your daughter. Hopefully, it will. It's just trial and error.
Humira was the anti-TNF I did best on, for both the Crohn's and the AS. The shots do hurt more than Enbrel, just as a head's up.
It's definitely more complex with the two diseases, but luckily, there are more options now that treat both -- Humira, Remicade, Cimzia, Simponi (off-label) and Stelara (which should be approved soon).
Last edited by CBMom; 07/10/16 09:55 PM.