I tried Voltaren gel a few times on my wrist several years ago, applying the measured amount four times a day as per the instructions. I was on daily Indomethacin at the time. Every time I tried the Voltaren gel, I would get tinnitus the second day, along with that weird head feeling you get when you take too much NSAID. Even though Voltaren gel is topical and I was nowhere near the maximum daily dose, enough was getting into my bloodstream to interact with the Indomethacin.
I haven't tried it now that I'm no longer on a daily NSAID. (I now take Celebrex as-needed.) I should try it again next time a joint flares up.
Ginny - 58 year old female
Dx with USpA in March 2013; changed to AS in July 2015
Iritis and Scleritis
unicompartmental knee replacements: right-June 2014, left-Aug 2018
MTX, Humira, Cyclobenzaprine, plus Celebrex as needed
Supplements: Folic Acid, Vitamin A, Vitamin D, Calcium, Fish Oil, Culturelle probiotic, Melatonin (as needed)