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#277724 - 04/11/17 03:30 PM Labwork
chelle2568 Offline
First time visitor

Registered: 04/06/17
Posts: 1
Brand new here. Just curious, will patients with AS have a positive ANA?

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#277726 - 04/11/17 06:12 PM Re: Labwork [Re: chelle2568]
Winston Online
Registered Visitor

Registered: 06/30/16
Posts: 188
Not always, but sometimes. ANA is more closely associated with lupus and Crohns, which AS sufferers will sometimes develop.

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#277733 - 04/13/17 12:57 PM Re: Labwork [Re: chelle2568]
Sheep1 Offline
Registered Visitor

Registered: 08/12/15
Posts: 210
I've developed ANA antibodies while on Humira, and my rheumatologist thinks it is the result of being on Humira. She said it's nothing to worry about for now.
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48 yo female, history of back pain since 1985, fatigue since 2009
-USpA diagnosis in August, 2015. Changed to PsA in 2016
-Erosions in finger joints
-HLA-B27 +
-Other: fibromyalgia dx in 2011 (wrong dx), endometriosis, severe pollen allergies
-Medications: Humira (since Oct, 2015). Weekly Humira start in Sept., 2016. Methotrexate (Dec. 2016). Aleve (as needed only), Lyrica, Tramadol, Baclofen, Vicoden, Tylenol, Xanax. Vitamin D, Vitamin B12, Folic Acid. Allergy Immunotherapy shots since 2009

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#277751 - 04/15/17 01:39 AM Re: Labwork [Re: chelle2568]
rumble Offline
Registered Visitor

Registered: 07/30/11
Posts: 219
Loc: Oklahoma USA
ANA can go up and down, positive sometimes and negative at others. It's not very specific, but when symptoms and a positive result come together, it could point the way for a rheumy. Usually mine is negative, but during a flare, it was positive to 1:80, which isn't really positive enough to mean anything at my lab. A good source of info for lab questions (besides asking a medical laboratory scientist or your doc) is www.labtestsonline.org, which is sponsored by a number of lab-oriented companies and accrediting agencies. Lots of good information to be found there.
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Psoriatic Arthritis, Osteoporosis HLAB27+
MTX, gabapentin, strontium citrate, and Mobic
Started Cimzia on 12/31/13
Already tried Remicade, Enbrel, Simponi, Humira

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