Posted By: sdot
Identical twins light the way for new genetic caus - 01/24/19 08:55 PM
Identical twin toddlers who presented with severe arthritis helped scientists to identify the first gene mutation that can single-handedly cause a juvenile form of this inflammatory joint disease. By investigating the DNA of individual blood cells of both children and then modelling the genetic defect in a mouse model, the research team was able to unravel the disease mechanism. https://www.sciencedaily.com/releases/2019/01/190124141644.htm
Posted By: kglenn
Re: Identical twins light the way for new genetic caus - 01/29/19 05:43 PM
I am an identical twin, so naturally my sister has been following my medical progression with great interest. So far, I have developed scleroderma with secondary Sjogren's and spondylitis. She also has symptoms of Sjogren's and antibodies for both RA and Lupus, but no significant symptoms of either and no spondylitis (so far).
I did find it amusing that the 'toddlers' in the article were quoted as saying "We are delighted to know that an explanation has been found for our illness and more so because we are sure it will help other children." Clearly the arthritis hasn't slowed down their cognition. LOL!
Posted By: achala
Re: Identical twins light the way for new genetic caus - 01/29/19 06:57 PM
sounds like Bruce Willis again... remake of Look Who is Talking (1989)?