I can't get off the celebrex either. I am going in for colonoscopy and upper GI in 2 weeks because of it. I actually only take 100mg per day but it also helps fatigue and depression. I have taken pretty much every NSAID out there except diclofenac. I have about five RX strength NSAIDS in my med collection. Meloxicam was what I took while working full time but now it messes with my stomach too much. The absolute best were Vioxx and Bextra. As for as side effects I worry more about my kidneys. My dad had had horrible ulcers from his naproxen habit. Danielle
I don't have anything to back it up other than what I had done over the years. Prior to my diagnosis of having AS symptoms for 20 years I took Advil, then I went on Dicofinac, then celbrex and bounced around on all of the medications. Out of those 20 years I took 6000-10000mg of advil a day for 14 years. Through blood work and other tests I have zero damage to my stomach, intestines, kidney and liver. Lucky? Genetics? I don't know. But I knew that taking this much in high doses would cause damage so I did take Gastro from AOR every day, Agmatine and Glycine. These three things claim to help protect you against damage from these types of medications.
That is VERY interesting. I wish I know about Agmatine and Glycine (probably Glutamine too) when I was prescribed tramadol after injuring my knee very badly (requiring a major surgical repair.) Three days after taking tramadol and my back pain started to become extremely evident. I even warned them that this was unwise to give me oral meds for pain...but NOOOOO...a regular citizen can't be well-informed about this kind of thing. lol
Agnatine is a great supplement. Reduces tolerance to morphine, opioids THC. Also it makes the THC stronger, last longer. It makes all pain and anti-inflammatory medications last 2-3 hours longer. I never noticed any side effects with the medications lingering longer in my system. Agnatine helps every so slightly with some nerve pain but its nothing special.
a few years ago I was able to uncover a study where they put agmatine into a solution and administered it through nasal. because I'm constantly reading reading up on and testing supplements. I do the best I can with safety in mind but sometimes things don't go as planned. I made my nasal solution from agmatine putting it into a nasal bottle and administered it that way. And wow did I go for a ride. I had an entire body Buzz for a few hours and then when I was taking my THC for sleep it was amplified by like by a lot it was really really strong. After the third night of administering agmatine this way rather than taking it orally I had to stop taking it nasally. it gave me vertigo really bad for almost a month. During the day I was fine but if I had my head tilted for too long on an angle and then moved I would get vertigo. waking up and getting out of bed I would topple over if I didn't give myself a minute to collect my head from spinning. But those symptoms subsided and i guesd why that study really never came to public or a way of administering agmatine. Taking it orally is the preferred way as they've been doing for a long time.
L-glutamine is a waste of time in my opinion. I found it aggravated my AS. I run a 100% clean diet when I test my supplements so that this way I know exactly what it's doing and doing this for 10 you're so tuned with your body you know exactly what's happening and why for the most part.
GLysine is a great amino acid that we do need. It helps with connective tissue repair and inflammation. But it's not groundbreaking . However I found it never really did anything for inflammation. What it has done for me was protect my stomach lining from medications and helps with sleep.
I also use it as a sweetener when I make a treat every few months. I make ice cream with 35% grass-fed sheep cream which is super high in nutrients out of all the milks and tastes awesome and the thickness is gorgeous because it's creamy, I add cherry tart powder which is freaking awesome for killing an AS flare up. Cherry tart powder compliments celebrex. During my journey I used to use as combination but I no longer do as I've come across better through my regime of supplements and diet. But again cherry tart powder is extremely effective. I add two eggs and two to three scoops of glycine as the sweetener. My wife uses glycine now when she bakes for the kids rather than use sugar. Glycine is healthy for you, we need it, so to have it an ice cream is a bonus. how awesome is it when you're getting a little bit of pain and you can have a bowl of ice cream and feel better from inflammation?
A new supplement I'm gearing up for is Butyrate. I'm going to be doing high doses of this supplement as it has been very promising for other autoimmune diseases and several other symptoms caused by the autoimmune disease such as depression, anxiety, ulcers, oxidative stress. From what I read like all supplements claim this is the Holy Grail. On a side note 905% of all supplements is a waste of money.