Hi @momchrisgr, not silly at all. After the anti-inflammatories failed, I brought up trying methotrexate or sulfasalazine before starting biologics, but my rheumy said they would not be helpful for my case. I just checked to see if I could find literature to back that up, and found this study: https://www.ncbi.nlm.nih.gov/pubmed/16583475.
The conclusions echo what she had told me: "Across all patients with AS, SSZ showed some benefit in reducing ESR and easing spinal stiffness, but no evidence of benefit in physical function, pain, spinal mobility, enthesitis, or patient and physician global assessment. Patients at an early stage of disease, with higher level of ESR (or active disease) and peripheral arthritis, might benefit from SSZ."
Every body is different, though. Did SSZ do anything for you?