Hi, that's a tough decision. What drug where you on when you were in remission for 15 years? Why did you stop? I'm not sure about the cost of drugs and access in America, as I'm in Europe but I would look for another drug to try, (not in a trial) if possible. Xeljanz is JAK inhibitor, like Rinvoq. Maybe you can try that? I was on Enbrel for 10 years. I developed really bad Psoriasis two years ago and have since tried Cosentyx, Xeljanz, Stelara, Infliximab, Infliximab w/ MTX, Infliximab w/ Otezla and I asked to go back to Xeljanz again, for a break, as it was the only one that did a little for my arthritis and skin. I'm about to start Simponi now. Still searching for one Biologic to work for both my conditions. Hope this gives you some insight.