Fatique was a major problem for me as well. I was a zombie and barely functional after work but I might have a fix your and everyone else that fixed 80% of mine.
AS wrecks havoc on you entire bodily fuctions and as a result the oxidative stress is a major cause of the chronic fatique.
Ubiquinol & L-Carnosine.
Your body naturally makes these 2 supplements. I figured out the sweet dosing spot trying different doses and read several studies to ensure too much wont have negative effects.
Take 400mg of Ubquinol in the morning, 500mg of L-Carnosine in the monring and another 500mg L-Carnosine before 4pm.
The reason for spacing out the Carnosine is that an enzyme quickly breaks it. Taking 1000mg a day allows it to stay in your system as the enzyme can't break it down fast enough and thus getting the benefits you need. **** DO NOT TAKE IF YOU ARE TAKING SATINES Medications**** Beyond that the 2 are perfectly safe and no side effects.
When you buy the Ubquinol make sure it is made with Olive oil as many come with Sunflower which is not good for those with AS. When you buy the L-Carnosine make sure it has no other supplements added such as Vitamin C in it.
I Take my supplements in powered forms because its cheaper and NO FILLERS. Mix the Ubquinol in olive oil as its a fat soluble. Meaning you cannot absorb it with out fat. The Carnosine is water soluble. The Ubquinol that you buy at the store is already mixed with Olive oil so no need to worry unless you buy it in pure crystal form as I do.
The recommended does of Ubquinol is 100mg but that is for a normal person and that dose will do nothing for you. Again Start off at 400mg.
Both of these supplements change everything. Here are 2 links to read up on and when you read it, it sounds too good to be true and for once it is true. You should notice something the same day but as the days go on you start to notice more and more changes.
Both of these supplements are not VEGAN free so your SOL. Ubquinol is derived from Yeast and Carnosine is from Meats/fishhttps://selfhacked.com/blog/ubiquinol-benefits/https://selfhacked.com/blog/carnosine/
I'm going to put putting together list of supplements that actually help you improve your quality of life and your welcome to contact me for information.