It is my understanding that it is very unusual to be diagnosed with AS (or spondyloarthropathy) if HLA-B27 negative. I have read some articles stating that some physicians will not even consider the diagnosis of AS if the test is negative. I suppose I am fortunate to have been diagnosed, even though it took many years of pain, and of course there was the fear of not knowing what was wrong with me.
I am curious to know how many other users of the message board are HLA-B27 negative. If you are, I would love to learn more about your story, if you feel comfortable enough to share.