I don't think there's a one size fits all answer - I guess you just have to try stuff and see how you respond and it could be different as it progresses or stops progressing.

For me I was diagnosed in 2011 and I run all the time competitively and found I could back off an all the meds by what seems like stomping out the inflammation with running. I took meloxicam for a few years after DX but decided to stop a while back to see what would happen and I haven't taken any meds for years now and run multiple marathons a year and shorter races often winning my age group with occasional ultramarathons and ironman and it all seems fine to me. Seems like the AS has gone dormant or maybe what I like to think is the constant exercising keeps it under control.